transmembrane protein deleted in velocardiofacial syndrome
Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Primary mouse lung endothelial cells were exposed to rabbit IgG (lane 2) or IL-1b (lane 3) for 24 hours. Lysates were analyzed by western blotting with an anti-mouse GAPDH antibody (1:2500) in 5% milk/TBST.
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