Claudin-11 Antibody - Pre-diluted

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Immunohistochemistry-Paraffin: Claudin-11 Antibody [NBP1-35660] - Human Testis stained with anti-Claudin-11 antibody

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Pre-diluted

Order Details

Claudin-11 Antibody - Pre-diluted Summary

Immunogen
A synthetic peptide derived from C-terminus of human claudin 11 protein
Specificity
This product is specific for Claudin 11
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CLDN11
Purity
IgM purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat
Application Notes
IHC-P: ready-to-use for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate, pH 6.0 for 10 min followed by cooling at RT for 20 min.Not tested in other applications.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Prediluted antibody with 50mM Tris (pH 7.6) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
IgM purified

Alternate Names for Claudin-11 Antibody - Pre-diluted

  • claudin 11
  • Claudin11
  • Claudin-11
  • CLDN11
  • Oligodendrocyte-specific protein
  • OSP
  • OSPOTMoligodendrocyte transmembrane protein
  • OTM

Background

Oligodendrocyte specific protein belongs is a major component of central nervous system myelin that is necessary for normal CNS function. The claudin superfamily consists of many structurally related proteins in humans. These proteins, which include claudin 1 through 18, and are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that the Claudin 11 protein determines the permeability between layers of myelin sheaths via focal adhesion and with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CLDN11
Entrez