Claudin-1 Antibody (SP128)

Images

 
Immunohistochemistry-Paraffin: Claudin-1 Antibody (SP128) [NBP1-74517] - Liver carcinoma
Flow Cytometry: Claudin-1 Antibody (SP128) [NBP1-74517] - Flow cytometric analysis of rabbit anti-Claudin-1 (SP128) antibody in HEPG2 (green) compare to negative control of rabbit IgG (blue)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
SP128
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Claudin-1 Antibody (SP128) Summary

Immunogen
Synthetic peptide corresponding to C-terminus of human claudin-1 protein.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CLDN1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:200
Theoretical MW
22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Predicted by homology: Mouse, Rat, Porcine, Bovine.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.6) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein A purified

Alternate Names for Claudin-1 Antibody (SP128)

  • claudin 1
  • Claudin1
  • Claudin-1
  • CLD1
  • CLDN1
  • ILVASCSenescence-associated epithelial membrane protein
  • SEMP1
  • SEMP1senescence-associated epithelial membrane protein 1

Background

Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for Claudin-1 Antibody (NBP1-74517). (Showing 1 - 1 of 1 FAQ).

  1. We are looking for two corresponding products, claudin 1 antibody and a peptide which can blocks the CLDN1.Could you plase kindly provide us solution for it? We found at your website one product, namely Claudin 1 Peptide ( NBP1-77036PEP),which can be used for blocking the activity of CLDN1. For the immunogen, 20 amino acids near the carboxy terminus of CLDN1 was mentioned. We found four Claudin 1 antibody ( NBP1-74546,NBP1-35652,NBP1-74517,H00009076-M1),and the immunogen was again the C-terminus of the Claudin 1.Cold you please send me more information about this C-terminus sequence?Is it the same in case of the NBP1-77036PEP and the four mentined antibodies?
    • The blocking peptide is a good purchase. The epitope for NBP1-35652 has not been mapped and the immunogen sequence is confidential, it is contained within the range between aa 140-211 of O95832 (Uniprot). Unfortunately NBP1-74517 has been discontinued. The amino acid sequence for H00009076-M01 is (AAH12471.1, 1 a.a. ~ 211 a.a). Unfortunately the lab that provides NBP1-74546 will not provide me with an aa range for the epitope as this is proprietary information that they are not willing to pass on.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CLDN1
Entrez