CKS1 Antibody

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Western Blot: Cks1 Antibody [NBP1-19583] - Jurkat cells treated with serum 20% 15'

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-19583
    • Availability
      Product Discontinued

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CKS1 Antibody Summary

Immunogen
Synthetic peptide, corresponding to the N-terminual of Human Cks1.
Clonality
Polyclonal
Host
Rabbit
Gene
CKS1B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of Cks1 (H3) pAb in extracts from Jurkat cells treated with serum 20% 15'.
Theoretical MW
9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CKS1 Antibody

  • CDC28 protein kinase 1
  • CDC28 protein kinase 1B
  • CDC28 protein kinase regulatory subunit 1B
  • cell division control protein CKS1
  • CKS-1
  • CKS1CDC2-associated protein CKS1
  • ckshs1
  • cyclin-dependent kinases regulatory subunit 1
  • NB4 apoptosis/differentiation related protein
  • PNAS-143
  • PNAS-16
  • PNAS-18

Background

The Cdc2 p34-cyclin B complex plays a critical role in the cell cycle by regulating the G2 to M transition. Also referred to as M-phase promoting factor or MPF, this complex is a required component of the cell cycle machinery and is necessary for cell entry into mitosis. The Cdc28 protein represents the S. cerevisiae counterpart of human Cdc2 p34 and has been found complexed to a regulatory protein, termed p13suc 1, in addition to cyclin B. The human homolog of p13suc 1 has been identified and designated Cks1 p9. Null mutations in the p13suc 1 and Cks1 p9 genes result in the arrest of the cell cycle at either the G1 or G2 phase, suggesting that the proteins may also regulate the activity of cyclin dependent kinases that act at critical points early in the cell cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CKS1B
Entrez
Uniprot