CHMP2B Antibody

Images

 
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. (anti-PCOLN3)

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-75178
    • Availability
      Product Discontinued

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CHMP2B Antibody Summary

Immunogen
The immunogen for this antibody was a sequence from 80a.a. to 196a.a. from CHMP2B(a 196a.a. long protein)
Localization
Membrane; multi-pass membrane protein.
Specificity
CHMP2B
Clonality
Polyclonal
Host
Chicken
Gene
CHMP2B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Reactivity Notes

This antibody is reactive against Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CHMP2B Antibody

  • charged multivesicular body protein 2b
  • CHMP2.5
  • CHMP2.5VPS2BVPS2-2
  • CHMP2B
  • chromatin modifying protein 2B
  • Chromatin-modifying protein 2b
  • DKFZP564O123
  • DMT1
  • hVps2-2
  • Vacuolar protein sorting-associated protein 2-2
  • vacuolar protein-sorting-associated protein 2-2
  • VPS2 homolog B
  • Vps2-2
  • VPS2B

Background

Component of the ESCRT-III complex. which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein PCGF4/BMI1 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing. In case of infection. the HIV-1 virus takes advantage of the ESCRT-III complex for budding and exocytic cargos of viral proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CHMP2B
Entrez
Uniprot