Recombinant Human CHMP2A Protein

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SDS-Page: CHMP2A Protein [NBP1-30206] - CHMP2A, 27.2 kDa (242aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human CHMP2A Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-222 of Human CHMP2A

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MDLLFGRRKT PEELLRQNQR ALNRAMRELD RERQKLETQE KKIIADIKKM AKQGQMDAVR IMAKDLVRTR RYVRKFVLMR ANIQAVSLKI QTLKSNNSMA QAMKGVTKAM GTMNRQLKLP QIQKIMMEFE RQAEIMDMKE EMMNDAIDDA MGDEEDEEES DAVVSQVLDE LGLSLTDELS NLPSTGGSLS VAAGGKKAEA AASALADADA DLEERLKNLR RD

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
CHMP2A
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
27.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH8.0) containing 0.1 M NaCl 1mM DTT, and 30% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human CHMP2A Protein

  • BC-2
  • BC2VPS2 homolog A
  • CHMP2a
  • CHMP2hVps2-1
  • chromatin modifying protein 2A
  • Chromatin-modifying protein 2a
  • Putative breast adenocarcinoma marker BC-2
  • Vacuolar protein sorting-associated protein 2-1
  • vps2-1
  • VPS2Aputative breast adenocarcinoma marker (32kD)
  • VPS2charged multivesicular body protein 2a

Background

CHMP2A, also known as chromatin modifying protein 2A, belongs to the SNF7 family and it is component of the ESCRT III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. Recombinant CHMP2A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol CHMP2A