Chk1 Antibody (2G1D2)

Images

 
Western Blot: Chk1 Antibody (2G1D2) [NBP1-19210] - HeLa and NIH/3T3 cell extracts. Lane 1: Molecular Weight Markers, Lane 2: HeLa, Lane 3: NIH/3T3

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
2G1D2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Chk1 Antibody (2G1D2) Summary

Immunogen
Recombinant human Chk1 protein
Specificity
Chk1 (2G1D2)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CHEK1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/ml
Publications
Read Publication using NBP1-19210.

Reactivity Notes

Human, Mouse, Rat. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 50% Glycerol
Preservative
0.09% Sodium Azide
Purity
Protein G purified

Alternate Names for Chk1 Antibody (2G1D2)

  • Checkpoint, S. pombe, homolog of, 1
  • CHEK1
  • CHK1 (checkpoint, S.pombe) homolog
  • CHK1 checkpoint homolog (S. pombe)
  • Chk1
  • CHK1serine/threonine-protein kinase Chk1
  • EC 2.7.11
  • EC 2.7.11.1

Background

The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation) induced degradation of cdc25A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Chk1 Antibody (NBP1-19210)(1)

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CHEK1
Entrez
Uniprot