CHD7 Recombinant Protein Summary
A recombinant protein corresponding to Human CHD7
Source: E. coli
Amino Acid Sequence: The amino acid sequence of this product is not available.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Sterile filtered and with no additives.
Reconstitute with deionized water to a final concentration of 1.0 mg/ml.
The purity of this protein is >95% pure by SDS-PAGE
Alternate Names for CHD7 Recombinant Protein
- ATP-dependent helicase CHD7
- chromodomain helicase DNA binding protein 7 isoform CRA_e
- chromodomain helicase DNA binding protein 7
- chromodomain-helicase-DNA-binding protein 7
- EC 3.6.1
- EC 22.214.171.124
DNA Binding Protein-7 (DBP-7) is a N-terminal His-tagged recombinant protein and a member of the Sso7d family of small, abundant, non-specific DNA-binding proteins from the hyperthermophilic Archea Sulfolobus. The 7-kDa protein from Sulfolobus spp. consists of a five stranded, incomplete Beta -barrel capped at the opening by a C-terminalalpha-helix; they bind to the minor groove of a DNA duplex via the triple-stranded Beta -sheet. The topology of the Sulfolobus 7-kDa proteins was found to be similar to that of chromatin organization modifier (chromo) domains and eukaryotic SH3 domains, which are involved in protein-protein interactions. In vitro studies have shown that DBP-7 promotes the annealing of complementary DNA strands, induces negative supercoiling and chaperones the disassembly and renaturation of protein aggregates in an ATP hydrolysis-dependent manner.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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