Western Blot: CES2 Antibody [NBP1-32653] - Sample (30 ug of whole cell lysate)A: Hep G2 7. 5% SDS PAGE diluted at 1:5000.
Immunocytochemistry/ Immunofluorescence: CES2 Antibody [NBP1-32653] - Sample: HepG2 cells were fixed in iced-cold MeOH for 5 min. Green: CES2 protein stained by CES2 antibody diluted at 1:500. Blue: Hoechst 33342 ...read more
62 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.