CDX2 Antibody

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Western Blot: CDX2 Antibody [NBP1-51181] Extracts from K562 cells.

Product Details

Summary
Product Discontinued
View other related CDX2 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-51181
    • Availability
      Product Discontinued

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CDX2 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 251-299 of Human CDX2.
Specificity
Cdx2 (Y80) pAb detects endogenous levels of Cdx2 (Y80) protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CDX2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
Western blot (WB) analysis of Cdx2 (Y80) pAb in extracts from K562 cells.
Theoretical MW
35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Cross reacts with Human, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CDX2 Antibody

  • caudal type homeo box transcription factor 2
  • caudal type homeobox 2
  • Caudal-type homeobox protein 2
  • CDX2
  • CDX3
  • CDX-3
  • CDX3caudal type homeobox transcription factor 2
  • homeobox protein CDX-2

Background

Cdx2, a homeobox domain-containing transcription factor, is a master regulator of the trophoectoderm, the layer that gives rise to extra-embryonic tissues in mammalian development. Cdx2 is also involved in intestinal development, and gain of expression or loss of expression has been associated with various human malignancies such as Barret Esophagus and colorectal cancer. Mouse embryonic stem cells deficient in Cdx2 display limited hematopoietic progenitor development and altered Hox gene expression, pointing to a role for Cdx2 in Hox gene regulation. Cdx2 is also implicated in the aberrant expression of Hox genes in human AML cell lines.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CDX2
Entrez