Recombinant Human CDC42BPB Protein

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SDS-Page: Recombinant CDC42BPB Protein [NBP1-99505]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE, HPLC
Concentration
0.1 mg/ml

Order Details

Recombinant Human CDC42BPB Protein Summary

Description
Recombinant protein for Human CDC42BPB

Source:Baculovirus (Sf9 insect cells)
Amino Acid Sequence:(NM_006035)

Source
Sf 9 (baculovirus)
Protein/Peptide Type
Biologically Active Protein
Gene
CDC42BPB
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Application Notes
Specific activity: The specific activity of MRCKB was determined to be 120 nmol /min/mg as per activity assay protocol.
Theoretical MW
73 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Concentration
0.1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human CDC42BPB Protein

  • CDC42 binding protein kinase beta (DMPK-like)
  • CDC42-binding protein kinase beta (DMPK-like)
  • CDC42-binding protein kinase beta
  • DMPK-like beta
  • EC 2.7.11
  • EC 2.7.11.1
  • FLJ37601
  • FLJ44730
  • KIAA1124DKFZp686H1431
  • MRCK beta
  • MRCKB
  • Myotonic dystrophy kinase-related CDC42-binding kinase beta
  • Myotonic dystrophy protein kinase-like beta
  • serine/threonine-protein kinase MRCK beta

Background

Myotonic Dystrophy Kinase-Related cdc42-binding kinase Beta (MRCKb) belongs to the DMPK subfamily (1). The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth (2). Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol CDC42BPB