CD98 Overexpression Lysate (Denatured)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB

Order Details

CD98 Overexpression Lysate (Denatured) Summary

Description
Pasmid: pCMV-SLC3A2 full-length
Gene
SLC3A2

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, and 0.01% Bromophenol blue).

Lysate Details for CD98

Type
Overexpression
Protein State
Denatured

Notes

Quality control test: Transient overexpression cell lysate was tested with Anti-SLC3A2 antibody by Western Blots.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CD98 Overexpression Lysate (Denatured)

  • 4F2
  • 4F2hc
  • 4T2HC
  • antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC
  • CD98 antigen
  • CD98 heavy chain
  • CD98
  • CD98HC
  • CH98hc
  • FRP-1
  • heavy chain
  • Lymphocyte activation antigen 4F2 large subunit
  • MDU1antigen defined by monoclonal 4F2, heavy chain
  • monoclonal 44D7
  • NACAE4F2 cell-surface antigen heavy chain
  • SLC3A2
  • solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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CD98 - cell surface glycoprotein that promotes cell adhesion, growth, and survival
CD98 is a heterodimeric glycoprotein that contains an 80 kDa heavy chain and a 40 kDa light chain. The CD98 heavy chain is also known as the 4F2 antigen heavy chain or FRP-1, and it is encoded by the SLC3A2 gene. The CD98 heavy chain is capable of...  Read full blog post.

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There are two opposing sides to the controversial cysteine/glutamate antiporter. On one hand, it can be viewed a guardian of the cell, protecting it from the damaging oxidative stress that can cause cell death and even cancer. But, conversely, it has...  Read full blog post.

Glutathione and xCT: Chemoresistance in Tumor Cells
Glutathione, called GSH in its reduced form and GSSG or L(-)-Glutathione in its oxidized form, is an endogenous antioxidant found in most cells in the body. Glutathione's functions include detoxifying xenobiotics from the body, assisting in membrane t...  Read full blog post.

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Bioinformatics

Gene Symbol SLC3A2
Entrez