CD7 Antibody (MEM-186) [FITC]

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Flow Cytometry: CD7 Antibody (MEM-186) [FITC] [NB500-370] - Surface staining of human peripheral blood cells with anti-human CD7 (MEM-186) FITC.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB500-370
    • Availability
      Product Discontinued

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CD7 Antibody (MEM-186) [FITC] Summary

Immunogen
Human acute myelogenous leukaemia cell line KG-1.
Specificity
The MEM-186 antibody reacts with CD7, a 40 kD type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia. HLDA VI; WS Code T 6T-015
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD7
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 20 ul/100 ul of whole blood or 10^6 cells in suspension
Positive Control
CD7 Lysate (NBL1-08964)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Purity
Protein A or G purified

Alternate Names for CD7 Antibody (MEM-186) [FITC]

  • CD7 antigen (p41)
  • CD7 antigen
  • CD7 molecule
  • CD7
  • GP40T-cell surface antigen Leu-9
  • LEU-9
  • T-cell antigen CD7
  • T-cell leukemia antigen
  • Tp40
  • TP41
  • TP41p41 protein

Background

CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CD7
Entrez