CD7 [p Ser124, p Ser123] Antibody (4H9) [FITC]

Images

 
Flow Cytometry: CD7 [p Ser124, p Ser123] Antibody (4H9) [FITC] [NBP2-00090] - Staining of normal human peripheral blood cells with Anti-Human CD4 PE and Mouse IgG2a kappa Isotype Control FITC (left) or Anti-Human CD7 ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP2-00090
    • Availability
      Product Discontinued

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CD7 [p Ser124, p Ser123] Antibody (4H9) [FITC] Summary

Immunogen
The immunogen for this antibody is CD7.
Modification
p Ser124, p Ser123
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CD7
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
This 4H9 antibody has been pre-titrated and tested by flow cytometric analysis on normal human peripheral blood cells. This can be used at 5 ul (0.125 ug)/per test. A test is defined as the amount (ug)/test of antibody that will stain a cell sample in a final volume of 100 uL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous buffer, may contain carrier protein/stabilizer (proprietary)
Preservative
0.09% Sodium Azide
Purity
Protein A or G purified

Alternate Names for CD7 [p Ser124, p Ser123] Antibody (4H9) [FITC]

  • CD7 antigen (p41)
  • CD7 antigen
  • CD7 molecule
  • CD7
  • GP40T-cell surface antigen Leu-9
  • LEU-9
  • T-cell antigen CD7
  • T-cell leukemia antigen
  • Tp40
  • TP41
  • TP41p41 protein

Background

This 4H9 monoclonal antibody reacts with human CD7 (also known as Leu-9 or gp40), a 40-kDa transmembrane glycoprotein belonging to the immunoglobulin superfamily. This molecule is expressed on peripheral blood T lymphocytes and natural killer cells, as well as on lymphoid and myeloid lineage precursors during adult hematopoiesis. Capable of providing a costimulatory signal and associating with CD3 and CD45, CD7 is involved in T cell activation. CD7 has also been detected on numerous T cell-derived leukemias and lymphomias. In fact, because CD7 expression is greater on CD4+ T cells in classical Hodgkin's lymphoma than in benign reactive lymph adenopathy, this molecule may be used as a diagnostic for Hodgkin's lymphoma. Blocking assays demonstrate that this clone recognizes the same epitope as clone 124-1D1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD7
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