CD7 Antibody (124-1D1)


Flow Cytometry: CD7 Antibody (124-1D1) [NBP1-43451] - Analysis using the Biotin conjugate of NBP1-43451. Staining of normal human peripheral blood cells with Anti-Human CD3 APC and 0.5 ug of Mouse IgG1 K Isotype Control more
Flow Cytometry: CD7 Antibody (124-1D1) [NBP1-43451] - Staining of normal human peripheral blood cells with 0.5 ug of Mouse IgG1 K Isotype Control Purified (open histogram) or 0.5 ug of Anti-human CD7 Purified (filled more

Product Details

Reactivity HuSpecies Glossary
Applications Flow

CD7 Antibody (124-1D1) Summary

The immunogen for this antibody was CD7.
Protein A or G purified
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  • Flow Cytometry 1:10-1:1000
Application Notes
This 124-1D1 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Reactivity Notes

This antibody is reactive to Human.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS (pH 7.2)
0.09% Sodium Azide
Protein A or G purified

Alternate Names for CD7 Antibody (124-1D1)

  • CD7 antigen (p41)
  • CD7 antigen
  • CD7 molecule
  • CD7
  • GP40T-cell surface antigen Leu-9
  • LEU-9
  • T-cell antigen CD7
  • T-cell leukemia antigen
  • Tp40
  • TP41
  • TP41p41 protein


The 124-1D1 monoclonal antibody reacts with human CD7, also known as gp40 and Leu9. CD7, a 40 kD receptor, is a member of the immunoglobulin gene superfamily. The N-terminal amino acid sequence (aa1-107) is highly homologous to Ig kappa light chain sequence while the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T lymphocytes, and T cell leukemias. It is also found on natural killer cells, a small suppopulation of normal B cells and on maligant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity, as measured by calcium flux, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3#39-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. A clonogenic subpopulation of human CD34(+) CD38(-) cord blood cells that express CD45RA and HLA-DR and high levels of the CD7 has been reported. These cells possess the capacity for lymphopoiesis. They can generate B-cells, natural killer cells, and dendritic cells but do not possess the capacity to develop into myeloid cells or erythroid cells. The CD7(+) phenotype distinguishes primitive human lymphoid progenitors from pluripotent stem cells. Furthermore, it has been suggested that CD7 co-operates with CD28 during Treg function, as mice deficient in both CD28 and CD7 have reduced total numbers of Tregs and these Tregs have reduced suppressive activity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-43451AF405
Alexa Fluor 488 Labeled NBP1-43451AF488
Alexa Fluor 647 Labeled NBP1-43451AF647
Alexa Fluor 700 Labeled NBP1-43451AF700
Allophycocyanin Labeled NBP1-43451APC
Biotin Labeled NBP1-43685
DyLight 350 Labeled NBP1-43451UV
DyLight 405 Labeled NBP1-43451V
DyLight 488 Labeled NBP1-43451G
DyLight 680 Labeled NBP1-43451FR
DyLight 755 Labeled NBP1-43451IR
PE Labeled NBP1-43451PE
PerCP Labeled NBP1-43451PCP

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Gene Symbol CD7