CD53 Antibody (MEM-53) [FITC] Summary
Leukocytes of pacient suffering from a LGL-type leukemia.
The antibody MEM-53 reacts with CD53, a 32-40 kDa tetraspanin family glycoprotein exclusivelly expressed on leukocytes; it is not present on platelets, red blood cells and non-hematopoietic cells. The antibody MEM-53 reacts also with deglycosylated molecule (molecular weight of the antigen is reduced by 15 kDa using endoglycosidase F). HLDA IV; WS Code NL 59 HLDA V; WS Code B CD53.5 HLDA V; WS Code BP BP287 HLDA V; WS Code T T-096 HLDA V; WS Code X XB004
Protein A purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.
Packaging, Storage & Formulations
Store at 4C in the dark.
PBS and 0.2% (w/v) high grade BSA (protease free)
15mM Sodium Azide
Protein A purified
Store in the dark. Avoid prolonged exposure to light.
Alternate Names for CD53 Antibody (MEM-53) [FITC]
- antigen MOX44 identified by monoclonal MRC-OX44
- CD53 antigentetraspanin-25
- CD53 glycoprotein
- CD53 molecule
- CD53 tetraspan antigen
- cell surface antigen
- Cell surface glycoprotein CD53
- MOX44transmembrane glycoprotein
- TSPAN25leukocyte surface antigen CD53
CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, Flow, CyTOF-ready, ICC
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
Applications: WB, ELISA, PLA
Species: Hu, Ca
Applications: WB, DB, EM, ELISA, Flow, Func, ICC/IF, IP
Applications: WB, ELISA, Flow, IHC, IHC-P, IF
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu, Gt, Pm, Sh
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P, IP, CyTOF-ready
Applications: WB, IHC, IHC-P
Species: Hu, Ca, GP
Applications: Flow, ICC/IF, IHC, IHC-Fr, IP
Applications: Flow, IP, CyTOF-ready
Applications: Flow, CyTOF-ready, ICC
Applications: WB, ELISA
Species: Hu, Mu, Rb(-)
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Applications: WB, ELISA, IHC
Applications: WB, Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vivo, CyTOF-ready
Applications: WB, ICC/IF, IHC, IHC-P
Publications for CD53 Antibody (NBP1-44793) (0)
There are no publications for CD53 Antibody (NBP1-44793).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for CD53 Antibody (NBP1-44793) (0)
There are no reviews for CD53 Antibody (NBP1-44793).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
- 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
FAQs for CD53 Antibody (NBP1-44793) (0)
Additional CD53 Products
Bioinformatics Tool for CD53 Antibody (NBP1-44793)
Discover related pathways, diseases and genes to CD53 Antibody (NBP1-44793). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on CD53.
CD81/TAPA1: I'm on Tapa the Cell
Target of the antiproliferative 1 (TAPA1), also known as CD81, is found in the plasma membrane in lymphocytes and plays an important role in the regulation of lymphoma cell growth. This transmembrane 4 superfamily (TM4SF) protein is primarily found on... Read full blog post.