CD5 Antibody (LT1)

Images

 
There are currently no images for CD5 Antibody (NB110-16583).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications B/N
Clone
LT1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

CD5 Antibody (LT1) Summary

Immunogen
Normal human blood lymphocytes
Localization
Type I membrane protein
Specificity
CD5 (LT1)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD5
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Blocking/Neutralizing 1:5000
Application Notes
Blocking: NB110-16583 can completely cross blocks binding of MAbs Leu1 and OKT1. It can also be used to enumerate T cells and classify cases of lymphoma.
Positive Control
CD5 Lysate (NBL1-08956)

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein G purified

Alternate Names for CD5 Antibody (LT1)

  • CD5 antigen (p56-62)
  • CD5 antigen
  • CD5 molecule
  • CD5
  • LEU1T-cell surface glycoprotein CD5
  • Lymphocyte antigen T1/Leu-1
  • T1

Background

In humans, CD5 is a 67kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
NBP2-24867
Species: Hu, Mu
Applications: Flow, Func, In vitro, In vivo, CyTOF-ready, Flow-CS
NBP1-19371
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
NBP1-49045
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, CyTOF-ready, InhibTFunc
NBP1-43435
Species: Hu, Mu
Applications: WB, Flow
H00054474-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP2-25196
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, In vitro, CyTOF-ready
NBP1-26666
Species: Mu
Applications: B/N, Flow, IP, In vitro
NBP2-15771
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
AF7579
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready, ICC
NB100-77417
Species: Mu
Applications: WB, Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P, IP, In vivo, CyTOF-ready
AF123
Species: Hu
Applications: WB, Block, ICC
NBP2-32840
Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF, IHC-P, IP
H00003669-M01
Species: Hu
Applications: WB, ELISA, ICC/IF

Publications for CD5 Antibody (NB110-16583) (0)

There are no publications for CD5 Antibody (NB110-16583).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CD5 Antibody (NB110-16583) (0)

There are no reviews for CD5 Antibody (NB110-16583). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

FAQs for CD5 Antibody (NB110-16583) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Additional CD5 Products

Bioinformatics Tool for CD5 Antibody (NB110-16583)

Discover related pathways, diseases and genes to CD5 Antibody (NB110-16583). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CD5 Antibody (NB110-16583)

Discover more about diseases related to CD5 Antibody (NB110-16583).
 

Pathways for CD5 Antibody (NB110-16583)

View related products by pathway.

PTMs for CD5 Antibody (NB110-16583)

Learn more about PTMs related to CD5 Antibody (NB110-16583).
 

Research Areas for CD5 Antibody (NB110-16583)

Find related products by research area.

Blogs on CD5

There are no specific blogs for CD5, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CD5 Antibody (LT1) and receive a gift card or discount.

Bioinformatics

Gene Symbol CD5
Entrez
Uniprot