CD46 Antibody Summary
Recombinant protein encompassing a sequence within the center region of human CD46. The exact sequence is proprietary.
Acrosome inner membrane; Single-pass type I membrane protein
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Western Blot 1:500-1:3000
- Immunocytochemistry/Immunofluorescence 1:100-1:1000
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Expected cross reactivity based on sequence homology: Rhesus Monkey (82%).
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
Immunogen affinity purified
Alternate Names for CD46 Antibody
- CD46 antigen
- CD46 molecule, complement regulatory protein
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- TLXcomplement regulatory protein
- trophoblast leucocyte common antigen
- Trophoblast leukocyte common antigen
- trophoblast-lymphocyte cross-reactive antigen
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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