CD45RA Antibody (MEM-56) [Allophycocyanin] Summary
Human thymocytes and T lymphocytes.
The antibody MEM-56 reacts with CD45RA, a 205-220 kDa single chain type I glycoprotein, variant of CD45 (CD45RA isoform). CD45RA is expressed on most of B lymphocytes, resting and native T lymphocytes, medullar thymocytes and monocytes. HLDA IV; WS Code NL 907
Protein A purified
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Packaging, Storage & Formulations
Store at 4C in the dark.
Allophycocyanin (A=620-650, E=660-670)
PBS and 0.2% (w/v) high grade BSA (protease free)
15mM Sodium Azide
Protein A purified
Alternate Names for CD45RA Antibody (MEM-56) [Allophycocyanin]
- CD45 antigen
- EC 126.96.36.199
- protein tyrosine phosphatase, receptor type, C
- receptor-type tyrosine-protein phosphatase C
- T200 glycoprotein
- T200 leukocyte common antigen
- T200receptor type, c polypeptide
CD45RA is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on nave T cells and normal plasma cells.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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