CD44 Antibody (156-3C11)

Product Discontinued

CD44 Antibody (156-3C11) Summary

• Immunogen: BALB/C mice were injected with stimulated human leukocytes.
• Epitope: Resistant to digestion by trypsin and chymotrypsin.1
• Localization: Cell Membrane
• Marker: Cell Membrane Marker
• Specificity: This antibody is specific to a cell surface glycoprotein of 80-95 kDa, known as CD44. CD44 is expressed on the surface of lymphocytes, monocytes and granulocytes. This antibody reacts with red cells pretreated with 2-aminoethlyl isothiouronium bromide (AET).
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD44
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin 1:25-1:75
• Application Notes: For IHC-P: Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID 26791217).

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM PBS (pH 7.4) and 0.2% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for CD44 Antibody (156-3C11)

• CD44 antigen
• CD44 molecule (Indian blood group)
• CD44
• CD44R
• CDw44
• cell surface glycoprotein CD44
• chondroitin sulfate proteoglycan 8
• CSPG8
• ECMR-III
• epican
• Extracellular matrix receptor III
• GP90 lymphocyte homing/adhesion receptor
• HCAM
• HCELL
• hematopoietic cell E- and L-selectin ligand
• Heparan sulfate proteoglycan
• Hermes antigen
• homing function and Indian blood group system
• HUTCH-I
• Hyaluronate receptor
• IN
• LHR
• MC56
• MDU2
• MDU2CD44 antigen (homing function and Indian blood group system)
• MDU3
• MDU3CDW44
• MIC4
• MIC4MGC10468
• MUTCH-I
• Pgp1
• PGP-1
• PGP-I
• Phagocytic glycoprotein 1
• Phagocytic glycoprotein I

Background

CD44 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. CD44 is also known as homing cell adhesion molecule (HCAM), Phagocytic glycoprotein-1 (PgP-1), ECM-III, HUTCH-1, or Hermes-1. CD44 has been implicated in cell migration, in lymphocyte homing, and in tumor metastasis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD44 Antibody (NB120-16728)(2)

Publications using NB120-16728

• Vinukonda G, Dohare P, Arshad A et al. Hyaluronidase and Hyaluronan Oligosaccharides Promote Neurological Recovery after Intraventricular Hemorrhage. J. Neurosci. 2016-01-20 [PMID: 26791217] (IHC-Fr, Human)
• Holderied A, Romoli S, Eberhard J et al. Glomerular parietal epithelial cell activation induces collagen secretion and thickening of Bowman's capsule in diabetes. Lab. Invest. 2014-12-22 [PMID: 25531564] (IHC-P, Human)

Review for CD44 Antibody (NB120-16728) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Ajit Singh IHC-P Human 10/27/2014

Summary

• Application: Immunohistochemistry-Paraffin
• Sample Tested: Breast cancer tissue
• Species: Human

FAQs for CD44 Antibody (NB120-16728). (Showing 1 - 1 of 1 FAQs).

1. Can you tell me the molecular weight for the following CD44 antibody, catalog # NB120-16728 (clone 156-3C11)?
   • The molecular weight of the antigen that this antibody binds to is a cell surface glycoprotein that is 80-95 kDa in size.

Bioinformatics

• Gene Symbol: CD44
• Entrez:
  • 960(Human)
• Uniprot:
  • P16070()