CD42b/GPIb alpha Antibody (AK2) [FITC]

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Flow Cytometry: CD42b/GPIb alpha Antibody (AK2) [FITC] [NB100-63793] - Staining of human peripheral blood platelets with MOUSE ANTI HUMAN CD42b:FITC

Product Details

Summary
Product Discontinued
View other related CD42b/GPIb alpha Primary Antibodies

Order Details


    • Catalog Number
      NB100-63793
    • Availability
      Product Discontinued

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CD42b/GPIb alpha Antibody (AK2) [FITC] Summary

Immunogen
Made to Human CD42b
Specificity
Recognises the human CD42b cell surface antigen, also known as platelet glycoprotein GP1B. CD42b is expressed by platelets and megakaryocytes. Clone AK2 has been reported to block the binding of von Willebrand Factor (VWF) to platelets (1).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GP1BA
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Theoretical MW
69 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein G purified

Alternate Names for CD42b/GPIb alpha Antibody (AK2) [FITC]

  • Antigen CD42b-alpha
  • BP1BA
  • BSS
  • CD42b antigen
  • CD42b
  • CD42b-alpha
  • glycoprotein Ib (platelet), alpha polypeptide
  • Glycoprotein Ibalpha
  • GP1B
  • GP1BA
  • GPIb alpha
  • GP-Ib alpha
  • GPIbA
  • GPIb-alpha
  • MGC34595
  • platelet glycoprotein Ib alpha chain
  • platelet membrane glycoprotein 1b-alpha subunit

Background

CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF. Clone AK2 has been reported to block the binding of von Willebrand Factor to platelets.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol GP1BA
Entrez