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CD41/CD61 Antibody (Gi5)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, Func, ICC/IF, IP, ELISA(Cap)
Clone
Gi5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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CD41/CD61 Antibody (Gi5) Summary

Immunogen
Human platelets.
Specificity
Recognizes CD41a (CD41/CD61 complex).
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGA2B
Purity
N/A
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Functional
  • Immunocytochemistry/Immunofluorescence
  • Immunoprecipitation
  • Sandwich ELISA Capture

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Purified antibody PBS
Preservative
0.05% Sodium Azide
Purity
N/A

Alternate Names for CD41/CD61 Antibody (Gi5)

  • CD41 antigen
  • CD41
  • CD41BHPA3
  • GP2Bintegrin alpha-IIb
  • GPalpha IIb
  • GPIIb
  • GTA
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41)
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41B)
  • ITGAB
  • platelet fibrinogen receptor, alpha subunit
  • Platelet membrane glycoprotein IIb
  • platelet-specific antigen BAK

Background

Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CD41/CD61 Antibody (Gi5)
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Bioinformatics

Gene Symbol ITGA2B