It stains the cell boundaries of endothelial cells with a staining pattern identical to that of silverstaining. Furthermore in histology it stains weakly histocytes and glomeruli. Useful for functional studies on cell-cell interactions; studies on integrity of endothelial cell monolayers; and the antibody can be used for immunoblotting under non reducing conditions.
Read 1 Review rated 4 using NBP1-42152 in the following applications:
CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells and is specifically concentrated at the junction between them. Therefore, CD31 antibodies are commonly used as endothelial markers to measure angiogenesis in association with tumor recurrence. It is also weakly expressed on many peripheral lymphoid cells and platelets. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
It is also weakly expressed on many peripheral lymphoid cells and platelets.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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