CD31/PECAM-1 Antibody (SP38)

Images

 
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Tonsil
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Colon Adenocarcinoma.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - CD31
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Lung Adenocarcinoma.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Esophagus.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Endometrium.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Lung stained.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Endometrial Adenocarcinoma.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Liver.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Liver Hepatocellular Carcinoma.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Heart.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Colon.
Immunohistochemistry-Paraffin: CD31/PECAM-1 Antibody (SP38) [NBP1-49805] - Human Cervix.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clone
SP38
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

CD31/PECAM-1 Antibody (SP38) Summary

Immunogen
Synthetic peptide corresponding to C-terminus of mouse CD31
Localization
Membrane
Specificity
CD31 is a glycoprotein expressed on endothelial cells and in platelets. It is known to be involved in cell signaling and cell adhesion.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PECAM1
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50
Application Notes
Molecular Weight: 100-130kDa
For IHC-P, antigen retrieval boil tissue section in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min. Immunocytochemistry/Immunofluorescence was reported in scientific literature.
Reviewed Applications
Read 1 Review rated 5
using
NBP1-49805 in the following applications:

Publications
Read Publications using
NBP1-49805 in the following applications:

  • 1 publication
  • IHC
    1 publication
  • WB
    1 publication

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Pig, Rat

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS (pH 7.5) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Tissue culture supernatant

Notes

For a positive control use Colon carcinoma.

Alternate Names for CD31/PECAM-1 Antibody (SP38)

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • endoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet/endothelial cell adhesion molecule

Background

CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells and is specifically concentrated at the junction between them. Therefore, CD31 antibodies are commonly used as endothelial markers to measure angiogenesis in association with tumor recurrence. It is also weakly expressed on many peripheral lymphoid cells and platelets. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas). It is also weakly expressed on many peripheral lymphoid cells and platelets.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD31/PECAM-1 Antibody (NBP1-49805)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: ICC/IF, IHC, WB.


Filter By Application
ICC/IF
(1)
IHC
(1)
WB
(1)
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Filter By Species
Mouse
(1)
All Species

Review for CD31/PECAM-1 Antibody (NBP1-49805) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.
We have 1 review tested in 1 application: IHC-Fr.

Reviews using NBP1-49805:
Filter by Applications
IHC-Fr
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
Immunohistochemistry-Frozen CD31/PECAM-1 NBP1-49805
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reviewed by:
Christopher England
IHC-Fr Mouse 09/01/2017
View

Summary

ApplicationImmunohistochemistry-Frozen
Sample Tested4T1 mouse breast cancer cell line
SpeciesMouse
LotNone

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for CD31/PECAM-1 Antibody (NBP1-49805) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CD31/PECAM-1 Products

Bioinformatics Tool for CD31/PECAM-1 Antibody (NBP1-49805)

Discover related pathways, diseases and genes to CD31/PECAM-1 Antibody (NBP1-49805). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CD31/PECAM-1 Antibody (NBP1-49805)

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PTMs for CD31/PECAM-1 Antibody (NBP1-49805)

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Research Areas for CD31/PECAM-1 Antibody (NBP1-49805)

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Blogs on CD31/PECAM-1.

The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...  Read full blog post.

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Christopher England
09/01/2017
Application: IHC-Fr
Species: Mouse

Bioinformatics

Gene Symbol PECAM1
Entrez
Uniprot