CD31/PECAM-1 Antibody (MEM-05) [PE]

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Flow Cytometry: CD31/PECAM-1 Antibody (MEM-05) [PE] [NBP1-44692] - Surface staining of human peripheral blood with anti-human CD31 (MEM-05) PE.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-44692
    • Availability
      Product Discontinued

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CD31/PECAM-1 Antibody (MEM-05) [PE] Summary

Immunogen
Tissue / cell preparation (Human). (Leucocytes of patient suffering from LGL-type leukaemia).
Specificity
This reacts with CD31 antigen.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PECAM1
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 ul reagent / 100 ul of whole blood or 10^6 cells in a suspension.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS and 0.2% (w/v) high grade BSA (protease free)
Preservative
15mM Sodium Azide
Purity
Protein A or G purified

Notes

Store in the dark. Avoid prolonged exposure to light.

Alternate Names for CD31/PECAM-1 Antibody (MEM-05) [PE]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • endoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet/endothelial cell adhesion molecule

Background

CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases. CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells. N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions. CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. It is one of key regulatory molecules in vascular system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional CD31/PECAM-1 Products

Bioinformatics Tool for CD31/PECAM-1 Antibody (NBP1-44692)

Discover related pathways, diseases and genes to CD31/PECAM-1 Antibody (NBP1-44692). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CD31/PECAM-1 Antibody (NBP1-44692)

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Pathways for CD31/PECAM-1 Antibody (NBP1-44692)

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PTMs for CD31/PECAM-1 Antibody (NBP1-44692)

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Research Areas for CD31/PECAM-1 Antibody (NBP1-44692)

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Blogs on CD31/PECAM-1.

The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...  Read full blog post.

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Bioinformatics

Gene Symbol PECAM1
Entrez