CD31/PECAM-1 Antibody (BV8) Summary
The antibody reacts with the CAM clone BV8 antigen.
This monoclonal antibody (subclaas IgG1) binds to human PECAM-1 (platelet endothelial cell adhesion molecule-1; CD31) a specific of endothelial cell junctions. It is also expressed in platelets and leukocytes.
Protein A or G purified
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- ELISA 1:100-1:2000
- Flow Cytometry 1:10-1:1000
- Immunoprecipitation 1:10-1:500
The antibody can be used for immunoassays, immunoprecipitation and flow cytometry.For flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS with 0.1% BSA
0.02% Sodium Azide
Protein A or G purified
Alternate Names for CD31/PECAM-1 Antibody (BV8)
- adhesion molecule
- CD31 antigen
- PECAM-1, CD31/EndoCAM
- platelet endothelial cell adhesion molecule
- platelet/endothelial cell adhesion molecule
CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed on the surface of endothelial cells and is specifically concentrated at the junction between them. Therefore, CD31 antibodies are commonly used as endothelial markers to measure angiogenesis in association with tumor recurrence. It is also weakly expressed on many peripheral lymphoid cells and platelets. Other studies have also indicated that CD31 and CD34 can be used as markers for myeloid progenitor cells and recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).
It is also weakly expressed on many peripheral lymphoid cells and platelets.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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