CD3 epsilon Antibody


Western Blot: CD3 epsilon Antibody [NBP1-31137] - Sample (30 ug of whole cell lysate) A: K562 12% SDS PAGE; antibody diluted at 1:1000.
Western Blot: CD3 epsilon Antibody [NBP1-31137] - MOLT4 12% SDS PAGE diluted at 1:1000

Product Details

Reactivity HuSpecies Glossary
Applications WB, DB
0.86 mg/ml

Order Details

CD3 epsilon Antibody Summary

Synthetic peptide corresponding to a region within amino acids 143 and 207 of CD3e (Uniprot ID#P07766)
Predicted Species
Porcine (100%), Rabbit (93%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at -20C. Avoid freeze-thaw cycles.
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0).
0.01% Thimerosal
0.86 mg/ml
Immunogen affinity purified

Reactivity Notes

Tested in human. Predicted cross-reactivity based on sequence identity: Mouse (87%), Rat (87%), Dog (87%), Cat (87%), Sheep (87%), and Bovine (80%). Not yet tested in any other species.

Alternate Names for CD3 epsilon Antibody

  • CD3e antigen
  • CD3e antigen, epsilon polypeptide (TiT3 complex)
  • CD3e molecule, epsilon (CD3-TCR complex)
  • CD3e
  • CD3-epsilon
  • FLJ18683
  • T3E
  • T-cell antigen receptor complex, epsilon subunit of T3
  • T-cell surface antigen T3/Leu-4 epsilon chain
  • T-cell surface glycoprotein CD3 epsilon chain
  • TCRE


CD3 complex is crucial in transducing antigen-recognition signals into the cytopasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies


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Contact Information

Product PDFs


Gene Symbol CD3E

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