CD25/IL-2 R alpha ELISA Kit Summary
|Standard Curve Range
0.31 - 20.0 ng/mL
Packaging, Storage & Formulations
Storage of components varies. See protocol for specific instructions.
The human sIL-2R ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human sIL-2R
- Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human sIL-2R
- HRP-Conjugate anti-human sIL-2R monoclonal antibody
- Human sIL-2R Standard lyophilized, 40 ng/ml upon reconstitution
- Sample Diluent
- Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
- Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
- Substrate Solution (tetramethyl-benzidine)
- Stop Solution (1M Phosphoric acid)
- Adhesive Films
Colored dyes for optional use with this kit are available and will be provided free of charge upon request. Please refer to catalog number NBP2-41404.
Alternate Names for CD25/IL-2 R alpha ELISA Kit
- CD25 antigen
- IL-2 R alpha
- IL-2 receptor subunit alpha
- IL2R alpha
- IL-2R subunit alpha
- interleukin 2 receptor, alpha
- interleukin-2 receptor subunit alpha
- TAC antigen
IL-2 has been described as a factor that promotes the growth and proliferation of human T-cells thus occupying a pivotal role in the generation of the immune response. This proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific cell surface receptor following T lymphocyte activation. The receptor for IL-2 is composed of at least three distinct polypeptide subunits, the IL-2R-alpha, IL-2R-beta, and the IL-2R-gamma chains giving rise to a 55-65 kD membrane bound protein. In addition to the de-novo expression of IL-2R by activated peripheral blood T-cells, a released and fully soluble form of IL-2R (sIL-2R) has been detected. It was shown that sIL-2R is present in vivo, at low levels in the sera of healthy persons and at markedly elevated levels in various pathological conditions like neoplastic disorders. Soluble IL-2R levels are significantly elevated in the sera of patients with adult T-cell leukemia, hairy cell leukemia, lymphocytic leukemia, Hodgkin's and Non-Hodgkin's lymphoma, liver, breast and lung cancer. In patients with systemic lupus erythematosus, rheumatoid arthritis, progressive systemic sclerosis, polymyositis, Kawasaki disease, multiple sclerosis, and Diabetes type I plasma concentrations of sIL-2 receptor are significantly elevated as compared to controls.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed
for 6 months from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu, Mu, Rt, Ca, Rb
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: Flow, IHC, ICC
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, Cell Depl, InhibTFunc
Applications: Flow, Func, In vitro, In vivo, Flow-CS
Applications: WB, IHC, IHC-P
Applications: Flow, IHC, Neut
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, S-ELISA
Applications: WB, ICC
Applications: WB, ELISA, IHC, IHC-P, PLA, S-ELISA
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Publications for CD25/IL-2 R alpha ELISA Kit (NBP1-88106) (0)
There are no publications for CD25/IL-2 R alpha ELISA Kit (NBP1-88106).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for CD25/IL-2 R alpha ELISA Kit (NBP1-88106) (0)
There are no reviews for CD25/IL-2 R alpha ELISA Kit (NBP1-88106).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
FAQs for CD25/IL-2 R alpha ELISA Kit (NBP1-88106) (0)
Additional CD25/IL-2 R alpha ELISA Kit Products
Related Products by Gene
Bioinformatics Tool for CD25/IL-2 R alpha ELISA Kit (NBP1-88106)
Discover related pathways, diseases and genes to CD25/IL-2 R alpha ELISA Kit (NBP1-88106). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on CD25/IL-2 R alpha