CD24 Antibody (30-F1) [Allophycocyanin]

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Product Details

Summary
Product Discontinued
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    • Catalog Number
      NBP1-28131
    • Availability
      Product Discontinued

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CD24 Antibody (30-F1) [Allophycocyanin] Summary

Immunogen
Mouse thymus or spleen
Specificity
Mouse CD24/heat stable antigen (HSA)
Isotype
IgG2c
Clonality
Monoclonal
Host
Rat
Gene
CD24
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Flow Cytometry < = 0.2 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS
Preservative
Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein A or G purified

Notes

Protect conjugated forms from light.

Alternate Names for CD24 Antibody (30-F1) [Allophycocyanin]

  • CD 24
  • CD24 antigen (small cell lung carcinoma cluster 4 antigen)
  • CD24 antigen
  • CD24 molecule
  • CD24
  • CD24A
  • CD24Asignal transducer CD24
  • FLJ22950
  • FLJ43543
  • MGC75043
  • Small cell lung carcinoma cluster 4 antigen

Background

CD24 is expressed in B cells until their terminal differentiation into plasma cells. (1) It has been used widely as a marker to fractionate different B-lineage differentiation stages. (10) CD24 has been found on a variety of other hematopoietic and neural cell types, and is now classified as a costimulatory molecule. (2-4) The CD24/HSA molecule is composed mostly of carbohydrate, with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. (1, 3) The molecular mass is variable, ranging from 38-70 kDa.3 CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. (1-4) Studies with purified CD24 applied to latex beads have demonstrated a self-binding property, suggesting that the molecule is capable of promoting homotypic aggregation, binding and cell adhesion. (3) This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with anti-CD24 monoclonal antibody. (6) Recent studies of murine CD24 have assigned a role for CD24/HSA as a ligand for P-selectin, a calcium-dependent lectin. (7)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Other Available Formats

PE Labeled NBP1-28130

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Bioinformatics

Gene Symbol CD24
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