CD23/Fc epsilon RII Antibody (2G8)

Images

 
Flow Cytometry: CD23/Fc epsilon RII Antibody (2G8) [NBP1-27907] - Analysis using the FITC conjugate of NBP1-27907. Multiple staining of BALB/c splenocytes.
Flow Cytometry: CD23/Fc epsilon RII Antibody (2G8) [NBP1-27907] - Analysis using the Biotin conjugate of NBP1-27907. Multiple staining of BALB/c splenocytes.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA, Flow, IHC-Fr, IP
Clone
2G8
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated

CD23/Fc epsilon RII Antibody (2G8) Summary

Immunogen
Fc-epsilon R isolated from B cell lymphoma cell line M12.4.5
Specificity
CD23 low affinity IgE Fc receptor
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
FCER2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Flow Cytometry <= 1 ug/10^6 cells
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunoprecipitation 1:10 - 1:500

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Purity
Protein A or G purified

Alternate Names for CD23/Fc epsilon RII Antibody (2G8)

  • BLAST-2
  • CD23
  • CD23A
  • CD23CD23 antigen
  • CLEC4J
  • CLEC4JC-type lectin domain family 4 member J
  • C-type lectin domain family 4, member J
  • Fc epsilon RII
  • Fc fragment of IgE, low affinity II, receptor for (CD23)
  • FCE2Fc fragment of IgE, low affinity II, receptor for (CD23A)
  • fc-epsilon-RII
  • FCER2
  • Fcer2a
  • FceRII
  • IGEBF
  • Immunoglobulin E-binding factor
  • low affinity immunoglobulin epsilon Fc receptor
  • Ly-42
  • Lymphocyte IgE receptor

Background

The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. (1) It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages and platelets. (1-6) It is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. (3) The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. (2-6) CD23 has been described as a 'membrane bound cytokine," in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro. (6)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF-386-PB
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
NB100-524
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, Flow-IC
H00003117-M01
Species: Hu
Applications: WB, ELISA, PLA
NBP2-02690
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
MAB4909
Species: Hu
Applications: WB, Flow, CyTOF-ready
NBP1-43435
Species: Hu, Mu
Applications: WB, Flow
H00054474-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
NBP2-25196
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, In vitro, CyTOF-ready
NBP2-15771
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
DDX0131P-100
Species: Hu
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
H00003669-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
NBP2-24867
Species: Hu, Mu
Applications: Flow, Func, In vitro, In vivo, CyTOF-ready, Flow-CS
NBP2-25250
Species: Hu, Mu
Applications: WB, Simple Western, ICC/IF, IHC, IHC-Fr, IHC-P
NBP1-27907
Species: Mu
Applications: ELISA, Flow, IHC-Fr, IP

Publications for CD23/Fc epsilon RII Antibody (NBP1-27907) (0)

There are no publications for CD23/Fc epsilon RII Antibody (NBP1-27907).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CD23/Fc epsilon RII Antibody (NBP1-27907) (0)

There are no reviews for CD23/Fc epsilon RII Antibody (NBP1-27907). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CD23/Fc epsilon RII Antibody (NBP1-27907) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-27907AF405
Alexa Fluor 488 Labeled NBP1-27907AF488
Alexa Fluor 647 Labeled NBP1-27907AF647
Alexa Fluor 700 Labeled NBP1-27907AF700
Allophycocyanin Labeled NBP1-27907APC
Biotin Labeled NBP1-27909
DyLight 350 Labeled NBP1-27907UV
DyLight 405 Labeled NBP1-27907V
DyLight 488 Labeled NBP1-27907G
DyLight 680 Labeled NBP1-27907FR
DyLight 755 Labeled NBP1-27907IR
FITC Labeled NBP1-27908
PE Labeled NBP1-27907PE
PerCP Labeled NBP1-27907PCP

Additional CD23/Fc epsilon RII Products

Bioinformatics Tool for CD23/Fc epsilon RII Antibody (NBP1-27907)

Discover related pathways, diseases and genes to CD23/Fc epsilon RII Antibody (NBP1-27907). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CD23/Fc epsilon RII Antibody (NBP1-27907)

Discover more about diseases related to CD23/Fc epsilon RII Antibody (NBP1-27907).
 

Pathways for CD23/Fc epsilon RII Antibody (NBP1-27907)

View related products by pathway.

Research Areas for CD23/Fc epsilon RII Antibody (NBP1-27907)

Find related products by research area.

Blogs on CD23/Fc epsilon RII

There are no specific blogs for CD23/Fc epsilon RII, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our CD23/Fc epsilon RII Antibody (2G8) and receive a gift card or discount.

Bioinformatics

Gene Symbol FCER2
Entrez