CD2 Antibody (OX-55)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-64855
    • Availability
      Product Discontinued

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CD2 Antibody (OX-55) Summary

Immunogen
Purified CD2 antigen
Localization
Type I membrane protein.
Specificity
NB100-64855 recognizes the rat CD2 antigen which is expressed on thymocytes and peripheral T cells. OX55 labels unidentified cells in the red pulp and marginal zone of spleen. OX55 when used with OX54 has a mitogenic effect on rat T-cells (1). Removal of sodium azide is recommended prior to use in functional assays.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500

Reactivity Notes

Reacts with Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for CD2 Antibody (OX-55)

  • CD2 antigen (p50), sheep red blood cell receptor
  • CD2 antigen
  • CD2 molecule
  • CD2
  • Erythrocyte receptor
  • FLJ46032
  • LFA-2
  • LFA-3 receptor
  • lymphocyte-function antigen-2
  • Rosette receptor
  • SRBC
  • T11
  • T-cell surface antigen CD2
  • T-cell surface antigen T11/Leu-5

Background

CD2 is a surface antigen of the human T lymphocyte lineage that is expressed on all peripheral blood T cells. It is one of the earliest T cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. CD2 interacts with lymphocyte function associated antigen (LFA3) and CD48/BCM1 to mediate adhesion between T cells and other cell types. CD2 is implicated in the triggering of T cells, the cytoplasmic domain is implicated in the signaling function. It is useful for the identification of lymphomas and leukaemias of T cell origin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for CD2 Antibody (NB100-64855). (Showing 1 - 1 of 1 FAQ).

  1. Is it a possibility to get 250ug of NB100-64855 (OX-55) antibody without sodium azide? I would like to conjugate it with biotin or fluorescent dye.
    • Unfortunately, we do not sell this product without sodium azide. If you are using our Lightning-Link labeling kits, sodium azide should only cause a negligible reduction in labeling efficiency. If you would like to remove the sodium azide and label it using your system, we have a number of antibody clean-up kits available.

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Bioinformatics

Gene Symbol CD2
Entrez
Uniprot