CD1b Antibody (CC14)

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Product Details

Summary
Reactivity Bv, Gt, ShSpecies Glossary
Applications Flow, IHC, IHC-Fr, IP
Clone
CC14
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

CD1b Antibody (CC14) Summary

Immunogen
Made to Bovine CD1w2
Specificity
This antibody recognizes the CD1 cell surface antigen in bovine, sheep and goat. The antibody immunoprecipitates two protein bands of 12kD and 46kD. In immunohistology the reagent stains cortical thymocytes and a minority of medullary thymocytes, with a pattern similar to antibodies of the CD1b cluster in humans.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD1B
Purity
Unpurified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:100
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:100
  • Immunoprecipitation 1:10-1:500

Reactivity Notes

Reacts with Bovine. Cross reacts with Goat and Sheep.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Ascites
Preservative
0.09% Sodium Azide
Purity
Unpurified

Alternate Names for CD1b Antibody (CC14)

  • CD1
  • CD1A
  • CD1b antigen
  • CD1B antigen, b polypeptide
  • CD1b molecule
  • CD1b
  • cortical thymocyte antigen CD1B
  • differentiation antigen CD1-alpha-3
  • MGC125990
  • MGC125991
  • R1
  • T-cell surface glycoprotein CD1b

Background

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CD1B
Entrez