CD16/CD32 Antibody (AP-MAB0815)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications B/N
Clone
AP-MAB0815
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

CD16/CD32 Antibody (AP-MAB0815) Summary

Immunogen
Mouse Macrophagess
Specificity
The was selected for its ability to detect mouse natural killer cells, monocytes, macrophages, dendritic cells (at low levels), Kupffer cells, granulocytes, mast cells, B lymphocytes, immature thymocytes, and some activated mature T lymphocytes.
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
FCGR3A
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Blocking/Neutralizing 50-200 molar excess

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
A 0.2 um filtered solution in PBS - Azide free
Preservative
No Preservative
Concentration
1.0 mg/ml
Purity
Protein A or G purified

Alternate Names for CD16/CD32 Antibody (AP-MAB0815)

  • CD16
  • CD16A
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • FCG3
  • FCGR3
  • FCGR3A
  • FCGRIII
  • FCR-10
  • FCRIII
  • FCRIIIA
  • IGFR3

Background

CD16 is the low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses. This antibody is specific to the common epitope of CD16/CD32. It is useful for blocking non-specific binding of immunoglobulin to the Fc receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional CD16/CD32 Products

CD16/CD32 NBP1-06653

Bioinformatics Tool for CD16/CD32 Antibody (NBP1-06653)

Discover related pathways, diseases and genes to CD16/CD32 Antibody (NBP1-06653). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CD16/CD32 Antibody (NBP1-06653)

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PTMs for CD16/CD32 Antibody (NBP1-06653)

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Blogs on CD16/CD32.

CD16 - Find me on macrophages, neutrophils and NK cells
CD16 is a lymphocyte Fc gamma type III low-affinity receptor for IgG and is represented by two similar genes, CD16A (Fc gamma RIII A) and CD16B (Fc gamma RIIIB). CD16A exists as a heterooligomeric polypeptide-anchored form in macrophages and NK cells....  Read full blog post.

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Bioinformatics

Gene Symbol FCGR3A
Entrez