CD15/Lewis X Antibody (29)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-2673
    • Availability
      Product Discontinued

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CD15/Lewis X Antibody (29) Summary

Immunogen
Fibronectin purified human monocytes.
Localization
Type II membrane protein. Membrane bound form in trans cisternae of Golgi.
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
FUT4
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10 - 1:1000
  • CyTOF-ready

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for CD15/Lewis X Antibody (29)

  • CD 15
  • CD15
  • CD-15
  • Lewis X
  • Lewis-X
  • LeX
  • SSEA-1
  • stage-specific embryonic antigen 1

Background

The CD15 antigen is expressed on approximately 90% human circulating granulocytes (membranes and granules), 30 to 60% of circulating monocytes and is absent from normal lymphocytes. CD15 antigen is also expressed on Reed Sternberg cells of Hodgkin's disease, on T cell lymphomas including mycosis fungoides and on some leukemias. Outside the hematopoietic system, CD15 expression is described in certain normal and neoplastic epithelial cells and in astrocytes. At least 5 major CD15 antigens (105, 135, 165, 185, 220 kDa) are present on the surface membranes of polymorphonuclear cells. The hapten occurs also in glycolipids. CD15 plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FUT4
Entrez