CD14 Antibody (LT14)



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CD14 Antibody (LT14) Summary

Normal human blood lymphocytes
Cytoplasmic. Attached to the membrane by a GPI anchor.
Reacts with CD14 antigen (MW 55 kDa).
Protein A or G purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
PBS pH 7.4
0.09% Sodium Azide
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Protein A or G purified


Application Notes
Immunoassay This antibody may be used to enumerate human monocytes and classify cases of lymphoma.

Reactivity Notes

Cross-reacts with Human.


CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Gene Symbol CD14

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