CD11c Antibody (N418) Summary
The immunogen for this antibody was CD11c.
Dendritic Cell Marker
Protein A or G purified
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Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Aqueous buffer, may contain carrier protein/stabilizer (proprietary).
0.09% Sodium Azide
Protein A or G purified
The N418 antibody has been tested by flow cytometric analysis of mouse splenocyte suspensions. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
Alternate Names for CD11c Antibody (N418)
- 95 alpha chain
- 95, alpha subunit
- CD11 antigen-like family member C
- CD11c antigen
- CD11Cleu M5, alpha subunit
- Integrin alpha X
- integrin alpha-X
- integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
- integrin, alpha X (complement component 3 receptor 4 subunit)
- Leu M5
- Leukocyte adhesion glycoprotein p150
- Leukocyte adhesion receptor p150
- leukocyte surface antigen p150
- myeloid membrane antigen, alpha subunit
- p150 95 integrin alpha chain
- p150,95 alpha
The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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