CD117/c-kit Antibody Summary
Synthetic 16 amino acid peptide from extracellular domain of human c-Kit.
Extracellular domain of human
Hematopoietic Stem Cell Marker
Human c-Kit. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Monkey (94%). Backed by our 100% Guarantee.
Immunogen affinity purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Immunohistochemistry-Paraffin 20 ug/ml
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%), Marmoset (88%), Mouse (88%), Rat (88%), Hamster (81%), Porcine (81%).
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1% Sodium Azide
Immunogen affinity purified
Alternate Names for CD117/c-kit Antibody
- CD117 antigen
- EC 2.7.10
- EC 220.127.116.11
- piebald trait
- Proto-oncogene c-Kit
- proto-oncogene tyrosine-protein kinase Kit
- SCF R
- SCFRmast/stem cell growth factor receptor
- soluble KIT variant 1
- Tyrosine-protein kinase Kit
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
- v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Somatic gain-of-function mutations in the extracellular domain, kinase domains 1 and 2 are found in gastrointestinal stromal tumors (GISTs). Mutations in c-KIT gene are also associated with mast cell disease, acute myelogenous lukemia, and piebaldism. Tyrosine kinase inhibitor STI571 has been shown to inhibit GIST cells that express mutated c-KIT.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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Additional CD117/c-kit Products
Bioinformatics Tool for CD117/c-kit Antibody (NB110-55526)
Discover related pathways, diseases and genes to CD117/c-kit Antibody (NB110-55526). Need help?
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Blogs on CD117/c-kit.
Do you see what I see? I c-Kit
The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene... Read full blog post.