CD117/c-kit Antibody (C117/370 + KIT/982 + KIT/983) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
C117/370 + KIT/982 + KIT/983
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

CD117/c-kit Antibody (C117/370 + KIT/982 + KIT/983) [DyLight 488] Summary

Immunogen
Recombinant human CD117 proteins
Localization
Cell surface and cytoplasmic
Marker
Marker for Gastrointestinal Stromal Tumors
Specificity
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Isotype
IgG1 Kappa/IgG1 Kappa/IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
KIT
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD117/c-kit Antibody (C117/370 + KIT/982 + KIT/983) [DyLight 488]

  • CD117 antigen
  • CD117
  • ckit
  • c-kit
  • EC 2.7.10
  • EC 2.7.10.1
  • KIT
  • PBT
  • piebald trait
  • Proto-oncogene c-Kit
  • proto-oncogene tyrosine-protein kinase Kit
  • SCF R
  • SCFR
  • SCFRmast/stem cell growth factor receptor
  • soluble KIT variant 1
  • Tyrosine-protein kinase Kit
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for CD117/c-kit Antibody (NBP2-47845G) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47845AF350
Alexa Fluor 405 NBP2-47845AF405
Alexa Fluor 488 NBP2-47845AF488
Alexa Fluor 532 NBP2-47845AF532
Alexa Fluor 594 NBP2-47845AF594
Alexa Fluor 647 NBP2-47845AF647
Alexa Fluor 700 NBP2-47845AF700
Alexa Fluor 750 NBP2-47845AF750
Allophycocyanin NBP2-47845APC
Biotin NBP2-47845B
DyLight 350 NBP2-47845UV
DyLight 405 NBP2-47845V
DyLight 488 NBP2-47845G
DyLight 550 NBP2-47845R
DyLight 594 NBP2-47845DL594
DyLight 650 NBP2-47845C
DyLight 680 NBP2-47845FR
DyLight 755 NBP2-47845IR
FITC NBP2-47845F
HRP NBP2-47845H
Janelia Fluor 549 NBP2-47845JF549
Janelia Fluor 646 NBP2-47845JF646
PE NBP2-47845PE
PerCP NBP2-47845PCP

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Bioinformatics Tool for CD117/c-kit Antibody (NBP2-47845G)

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Blogs on CD117/c-kit.

Do you see what I see? I c-Kit
The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene...  Read full blog post.

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Bioinformatics

Gene Symbol KIT