CD117/c-kit Antibody (8D7D4)

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Western Blot: CD117/c-kit Antibody (8D7D4) [NB110-89462] - Analysis using KLK3 mAb against human KLK3 (AA: 109-216) recombinant protein. (Expected MW is 37.2 kDa)

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB110-89462
    • Availability
      Product Discontinued

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CD117/c-kit Antibody (8D7D4) Summary

Immunogen
Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3)
Marker
Hematopoietic Stem Cell Marker
Specificity
C-Kit (8D7D4)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
KIT
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500 - 1:2000
  • ELISA 1:10000
  • Immunohistochemistry 1:200 - 1:1000

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
0.03% Sodium Azide
Purity
Protein A purified

Alternate Names for CD117/c-kit Antibody (8D7D4)

  • CD117 antigen
  • CD117
  • ckit
  • c-kit
  • EC 2.7.10
  • EC 2.7.10.1
  • KIT
  • PBT
  • piebald trait
  • Proto-oncogene c-Kit
  • proto-oncogene tyrosine-protein kinase Kit
  • SCF R
  • SCFR
  • SCFRmast/stem cell growth factor receptor
  • soluble KIT variant 1
  • Tyrosine-protein kinase Kit
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
  • v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

Background

C-kit (CD117,145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for CD117/c-kit Antibody (NB110-89462)

Discover related pathways, diseases and genes to CD117/c-kit Antibody (NB110-89462). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CD117/c-kit Antibody (NB110-89462)

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PTMs for CD117/c-kit Antibody (NB110-89462)

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Research Areas for CD117/c-kit Antibody (NB110-89462)

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Blogs on CD117/c-kit.

Do you see what I see? I c-Kit
The c-Kit (CD117) proto-oncogene is a 145 kD receptor tyrosine kinase family closely related to platelet-derived growth factor receptor (PDGFR). It is a transmembrane receptor and the cellular homolog of the HZ4-feline sarcoma virus transforming gene...  Read full blog post.

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Bioinformatics

Gene Symbol KIT
Entrez