CCR3 Antibody (5E8-G9-B4)

Images

 
Flow Cytometry: CCR3 Antibody (5E8-G9-B4) [NBP1-43337] - Analysis using the PE conjugate of NBP1-43337. Analysis of normal human peripheral blood using CCR3 PE. This can be used at less than or equal to 1 ug per test. ...read more
Flow Cytometry: CCR3 Antibody (5E8-G9-B4) [NBP1-43337] - Staining of normal human peripheral blood cells with 0.5 ug of Mouse IgG2b kappa Isotype Control Purified (left) or 0.5 ug of Anti-Human CD193 (CCR3) Purified ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
5E8-G9-B4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
0.5 mg/ml

CCR3 Antibody (5E8-G9-B4) Summary

Immunogen
The immunogen for this antibody was CCR3.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CCR3
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
This 5E8-G9-B4 (5E8-G9-B4) antibody has been tested by flow cytometric analysis of normal human peripheral blood. This can be used at less than or equal to 1 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for CCR3 Antibody (5E8-G9-B4)

  • b-chemokine receptor
  • CC chemokine receptor 3
  • C-C chemokine receptor type 3
  • C-C CKR-3
  • CCR3
  • CCR-3
  • CD193 antigen
  • CD193
  • chemokine (C-C motif) receptor 3
  • CKR3CC-CKR-3CMKBR3CD193
  • eosinophil CC chemokine receptor 3
  • Eosinophil eotaxin receptor
  • MGC102841

Background

The 5E8-G9-B4 monoclonal antibody reacts with human CD193 (CCR3, CKR3). CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. CD193 can also serve as a receptor for HIV-1 cell entry.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CCR3
Entrez