CCM2 Antibody

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Western Blot: CCM2 Antibody [NBP1-47189]
Immunocytochemistry/ Immunofluorescence: CCM2 Antibody [NBP1-47189] - Human foreskin (cryo-section of unfixed tissue) with anti-human CCM2-K5546 ( dilution 1:50). A) Note specific staining in the wall of microvessels. ...read more

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-47189
    • Availability
      Product Discontinued

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CCM2 Antibody Summary

Immunogen
anti-human CCM-2
Specificity
The polyclonal antibody will detect recombinant human CCM-2 in WB and native CCM-2 in IHC
Clonality
Polyclonal
Host
Rabbit
Gene
CCM2
Purity
Protein A purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1-5 ug/ml
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
Western blotting: Use at 1-5 micrograms/milliliter IHC: The antibody has been tested for immunohistochemistry-paraffin

Reactivity Notes

Reactive to human CCM-2

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for CCM2 Antibody

  • C7orf22OSM
  • cerebral cavernous malformation 2
  • Cerebral cavernous malformations 2 protein
  • chromosome 7 open reading frame 22
  • malcavernin
  • MGC4067
  • MGC4607
  • MGC74868

Background

p16 INK4a is a tumor suppressor protein. It is a specific inhibitor of Cdk 4 / Cdk 6, and a tumor suppressor involved in the pathogenesis of a variety of malignancies. Recent analyses of the p16 INK4a gene revealed homozygous deletions, nonsense, missense, or frameshift mutations in several human cancers. Although the frequency of p16 INK4a abnormalities is higher in tumor derived cell lines than in unselected primary tumors, significant subsets of clinical cases with aberrant p16 INK4a gene have been reported among melanomas, gliomas, esophageal, pancreatic, lung, and urinary bladder carcinomas, and some types of leukemia.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional CCM2 Products

Bioinformatics Tool for CCM2 Antibody (NBP1-47189)

Discover related pathways, diseases and genes to CCM2 Antibody (NBP1-47189). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CCM2 Antibody (NBP1-47189)

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Pathways for CCM2 Antibody (NBP1-47189)

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PTMs for CCM2 Antibody (NBP1-47189)

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Blogs on CCM2

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol CCM2
Uniprot