Recombinant Rat CCL2/MCP1 Protein

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications PAGE, HPLC
Concentration
Lyoph

Order Details

Recombinant Rat CCL2/MCP1 Protein Summary

Description
Recombinant bioactive protein containing 125 amino acids for Rat CCL2/MCP1

Source:E. coli
Amino Acid Sequence:(P14844)

Preparation
Method
>98% SDS-PAGE
Details of Functionality
Determined by its ability to chemoattract human monocytes using a concentration range of 10-100 ng/ml.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
CCL2
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
14 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and then lyophilized with no additives. The protein may appear as a haze or film which is difficult to see at the bottom of the vial.
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute in H2O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other buffered solutions and stored at 4C for 1 week or -20C for future use.

Alternate Names for Recombinant Rat CCL2/MCP1 Protein

  • C-C motif chemokine 2
  • chemokine (C-C motif) ligand 2
  • GDCF-2
  • HC11Monocyte secretory protein JE
  • MCAFMonocyte chemotactic and activating factor
  • MCP1 Monocyte chemotactic protein 1
  • MCP-1 Small-inducible cytokine A2
  • MGC9434
  • Monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • SCYA2HSMCR30
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • SMC-CF

Background

Macrophage/monocyte chemoattractant protein-1 (MCP-1) plays an important role in the inflammatory response of blood monocytes and tissue microphages. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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MCP-1 - chemoattractant protein involed in monocyte migration and infiltration
Monocyte chemotractant protein-1 (MCP-1), also known as CCL2, is a key chemokine involved in the migration of monocytes and macrophages to sites of active inflammation. It is a member of the C-C/beta family of cytokines, characterized by the Cys-C...  Read full blog post.

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Bioinformatics

Gene Symbol CCL2