Recombinant Human CCL2/MCP1 Protein

Images

 
Flow Cytometry: CCL2/MCP1 Partial Recombinant Protein [NBP1-43186] - Analysis using the FITC conjugate of NBP1-43186. Staining of 1-day LPS-stimulated human peripheral blood cells with 0.5 ug of Armenian Hamster IgG ...read more
Functional: CCL2/MCP1 Partial Recombinant Protein [NBP1-43186] - Analysis using the Biotin conjugate of NBP1-43186. Staining of mouse thiogylcolate induced peritoneal exudate cells (PECs) stimulated with LPS in the ...read more

Product Details

Summary
Product Discontinued
View other related CCL2/MCP1 Peptides and Proteins

Order Details


    • Catalog Number
      NBP1-43186
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

Recombinant Human CCL2/MCP1 Protein Summary

Description
A partial protein corresponding to amino acids 2H5 of CCL2.
Details of Functionality
Measured by chemotaxis assay of human monocytes. Maximal chemoattractant activity was observed between 10-100 ng/ml.
Protein/Peptide Type
Partial Recombinant Protein
Gene
CCL2
Purity
Immunogen affinity purified

Applications/Dilutions

Application Notes
This recombinant human CCL2 has been tested in bioassays for chemoattractant activity. Measured by chemotaxis assay of human monocytes, the maximal chemoattractant activity was observed between 10-100 ng/ml.

Reactivity Notes

Mouse, Rat, Human.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
Sterile liquid, phosphate buffered saline, pH 7.2, with 1.0% BSA. 0.22 um filtered.
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

Purity: Greater than 98%, as determined by SDS-PAGE

Alternate Names for Recombinant Human CCL2/MCP1 Protein

  • C-C motif chemokine 2
  • chemokine (C-C motif) ligand 2
  • GDCF-2
  • HC11Monocyte secretory protein JE
  • MCAFMonocyte chemotactic and activating factor
  • MCP1 Monocyte chemotactic protein 1
  • MCP-1 Small-inducible cytokine A2
  • MGC9434
  • Monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • SCYA2HSMCR30
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • SMC-CF

Background

CCL2, also known as Monocyte Chemotactic Protein-1 (MCP-1) and Monocyte Chemotactic and Activating Factor (MCAF), is a member of the (CC) subfamily of chemokines. CCL2 is a chemoattractant for monocytes and regulates their adhesion molecule and cytokine expression patterns. It has also been shown to activate monocytes to be cytostatic for some human tumor cell lines. CCL2 is also capable of chemoattracting, activating and inducing histamine release from basophils. Recombinant human CCL2 produced inE. coli is a non-glycosylated peptide chain of 76 amino acids.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Customers Who Viewed This Item Also Viewed...

MAB208
Species: Hu
Applications: WB, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
NBP1-48337
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NBP2-29323
Species: Hu, Mu, Rt, Bv, Ca, Ch, Xp
796-IC
Species: Mu
MAB2005
Species: Hu
Applications: WB, Flow, CyTOF-ready
AF7177
Species: Hu
Applications: WB, ICC
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NBP1-43186
Species: Hu
Applications: Flow, Func, IA

Publications for CCL2/MCP1 Protein (NBP1-43186) (0)

There are no publications for CCL2/MCP1 Protein (NBP1-43186).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for CCL2/MCP1 Protein (NBP1-43186) (0)

There are no reviews for CCL2/MCP1 Protein (NBP1-43186). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCL2/MCP1 Protein (NBP1-43186). (Showing 1 - 1 of 1 FAQ).

  1. I am interested in one of your products - MCP1 Protein (NBP1-43186). The description provided noted this is a partial protein generated from Gln34-Thr99 of the human MCP-1 protein (full length is 99 amino acids). I looked at the amino acid sequence, and found aa 34 is a Cys, not a Gln residue. However, aa 24 is a Gln residue. Can you clarify this issue? Also, can you comment on purity?
    • The purity is greater than 98% as determined by endotoxin levels. I can now confirm that the AA Sequence of the Human MCP-1 is QPDAINAPVTTQTPKT which is Gln 24 - Thr 99. I have corrected this on the datasheet as well and wanted to thank you for pointing out this error which allowed us to go back and fix it.

Additional CCL2/MCP1 Products

Bioinformatics Tool for CCL2/MCP1 Protein (NBP1-43186)

Discover related pathways, diseases and genes to CCL2/MCP1 Protein (NBP1-43186). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for CCL2/MCP1 Protein (NBP1-43186)

Discover more about diseases related to CCL2/MCP1 Protein (NBP1-43186).
 

Pathways for CCL2/MCP1 Protein (NBP1-43186)

View related products by pathway.

PTMs for CCL2/MCP1 Protein (NBP1-43186)

Learn more about PTMs related to CCL2/MCP1 Protein (NBP1-43186).
 

Research Areas for CCL2/MCP1 Protein (NBP1-43186)

Find related products by research area.

Blogs on CCL2/MCP1.

MCP-1 - chemoattractant protein involed in monocyte migration and infiltration
Monocyte chemotractant protein-1 (MCP-1), also known as CCL2, is a key chemokine involved in the migration of monocytes and macrophages to sites of active inflammation. It is a member of the C-C/beta family of cytokines, characterized by the Cys-C...  Read full blog post.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Recombinant Human CCL2/MCP1 Protein and receive a gift card or discount.

Bioinformatics

Gene Symbol CCL2