CCL2/MCP1 Partial Recombinant Protein Summary
A partial protein corresponding to amino acids 2H5 of CCL2.
|Details of Functionality
Measured by chemotaxis assay of human monocytes. Maximal chemoattractant activity was observed between 10-100 ng/ml.
Immunogen affinity purified
Packaging, Storage & Formulations
Store at -80C. Avoid freeze-thaw cycles.
Sterile liquid, phosphate buffered saline, pH 7.2, with 1.0% BSA. 0.22 um filtered.
0.09% Sodium Azide
Immunogen affinity purified
- Flow Cytometry
This recombinant human CCL2 has been tested in bioassays for chemoattractant activity. Measured by chemotaxis assay of human monocytes, the maximal chemoattractant activity was observed between 10-100 ng/ml.
Purity: Greater than 98%, as determined by SDS-PAGE
Alternate Names for CCL2/MCP1 Partial Recombinant Protein
- C-C motif chemokine 2
- chemokine (C-C motif) ligand 2
- HC11Monocyte secretory protein JE
- MCAFMonocyte chemotactic and activating factor
- MCP1 Monocyte chemotactic protein 1
- MCP-1 Small-inducible cytokine A2
- Monocyte chemoattractant protein 1
- monocyte chemoattractant protein-1
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
- small inducible cytokine subfamily A (Cys-Cys), member 2
CCL2, also known as Monocyte Chemotactic Protein-1 (MCP-1) and Monocyte Chemotactic and Activating Factor (MCAF), is a member of the (CC) subfamily of chemokines. CCL2 is a chemoattractant for monocytes and regulates their adhesion molecule and cytokine expression patterns. It has also been shown to activate monocytes to be cytostatic for some human tumor cell lines. CCL2 is also capable of chemoattracting, activating and inducing histamine release from basophils. Recombinant human CCL2 produced inE. coli is a non-glycosylated peptide chain of 76 amino acids.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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FAQs for CCL2/MCP1 Protein (NBP1-43186). (Showing 1 - 1 of 1 FAQ).
I am interested in one of your products - MCP1 Protein (NBP1-43186). The description provided noted this is a partial protein generated from Gln34-Thr99 of the human MCP-1 protein (full length is 99 amino acids). I looked at the amino acid sequence, and found aa 34 is a Cys, not a Gln residue. However, aa 24 is a Gln residue. Can you clarify this issue? Also, can you comment on purity?
- The purity is greater than 98% as determined by endotoxin levels. I can now confirm that the AA Sequence of the Human MCP-1 is QPDAINAPVTTQTPKT which is Gln 24 - Thr 99. I have corrected this on the datasheet as well and wanted to thank you for pointing out this error which allowed us to go back and fix it.
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