Alternate Names for CCL2/MCP1 Antibody (ECE.2) [Biotin]
C-C motif chemokine 2
chemokine (C-C motif) ligand 2
HC11Monocyte secretory protein JE
MCAFMonocyte chemotactic and activating factor
MCP1 Monocyte chemotactic protein 1
MCP-1 Small-inducible cytokine A2
Monocyte chemoattractant protein 1
monocyte chemoattractant protein-1
small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
small inducible cytokine subfamily A (Cys-Cys), member 2
Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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