Recombinant Mouse CCL11/Eotaxin Protein

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications PAGE
Concentration
Lyoph

Order Details

Recombinant Mouse CCL11/Eotaxin Protein Summary

Description
Recombinant bioactive protein containing 74 amino acids for Mouse CCL11/Eotaxin

Source:E. coli
Amino Acid Sequence:(P48298)

Preparation
Method
Determined to be >98% pure by SDS-PAGE
Details of Functionality
The recombinant murine eotaxin was found to induce chemotaxis of purified eosinophils at concentrations ranging between 100 to 1000 ng/ml.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
CCL11
Purity
>95%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
8.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20 to -80C. Avoid freeze-thaw cycles.
Buffer
Sterile filtered and then lyophilized with no additives. The protein may appear as a haze or film that is difficult to see at the bottom of the vial.
Concentration
Lyoph
Purity
>95%, by SDS-PAGE
Reconstitution Instructions
Reconstitute in H2O to a concentration of 0.1-1 ug/ul. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.

Alternate Names for Recombinant Mouse CCL11/Eotaxin Protein

  • C-C motif chemokine 11
  • CCL11
  • chemokine (C-C motif) ligand 11
  • Eosinophil chemotactic protein
  • Eotaxin
  • eotaxin-1
  • MGC22554
  • SCYA11Small-inducible cytokine A11
  • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

Background

Murine eotaxin shares many of the biological and physical characteristics of human eotaxin. The chemokine exhibits a high chemotactic selectivity for eosinophils and belongs to the C-C family of chemokines, along with chemokines such as RANTES, MCP-3, and MIP-1alpha. Murine eotaxin is an 8.4 kDa protein containing 74 amino acid residues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol CCL11
Entrez