Caveolin-1 Antibody (SP43)

Images

 
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human HK Lymphoma
Immunohistochemistry-Paraffin: Caveolin 1 Antibody (SP43) [NBP1-49807] - Caveolin-1
Immunohistochemistry-Paraffin: Caveolin 1 Antibody (SP43) [NBP1-49807] Human Lung Carcinoma
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Placenta
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Liver Hepatocellular Carcinoma
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Lung
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Skeletal Muscle
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Liver
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Cerebellum
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Cerebral Cortex
Immunohistochemistry-Paraffin: Caveolin-1 Antibody (SP43) [NBP1-49807] - Human Colon

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IHC-P
Clone
SP43
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Caveolin-1 Antibody (SP43) Summary

Immunogen
Synthetic peptide corresponding to C-terminus of human Caveolin 1 protein
Marker
Caveolae Marker, Endosome Marker
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
CAV1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

May also react with Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
7.0 ml prediluted antibody with 10mM PBS (pH 7.4) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein G purified

Notes

For a positive control use Breast carcinoma.

Alternate Names for Caveolin-1 Antibody (SP43)

  • CAV
  • CAV1
  • caveolae protein, 22kD
  • caveolin 1, caveolae protein, 22kDa
  • Caveolin1
  • Caveolin-1
  • cell growth-inhibiting protein 32
  • MSTP085
  • VIP21

Background

Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Caveolin-1 Antibody (NBP1-49807). (Showing 1 - 1 of 1 FAQ).

  1. Does the SP43 antibody recognize Cav2? And Cav1 Beta isoform?
    • Product NBP1-49807 has not yet been tested for cross reaction with Caveolin 2. The sequence used for the immunogen is from the C-terminal region of the human CAV1 protein, which is homologous with the beta isoform. I would therefore expect that this product would be able to detect both CAV1 alpha and beta forms. Based on an alignment with the CAV2 sequence, there were not any regions with significant homology, so I would not expect this product to detect the CAV2 protein.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CAV1
Entrez