Cav1.2 Antibody [HRP]

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Product Details

Summary
Product Discontinued
View other related Cav1.2 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-42820H
    • Availability
      Product Discontinued

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Cav1.2 Antibody [HRP] Summary

Immunogen
Synthetic peptide made to an internal portion of rat CACNA1C (within residues 1150-1200). [Swiss-Prot# P22002]
Localization
Membrane; Multi-pass membrane protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CACNA1C
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This Cav1.2 antibody is useful for Blocking/Neutralizing, Western blot and Immunoprecipitation. In WB a band can be seen at ~250 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
250 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Readout System

Reactivity Notes

Human, mouse, rat, rabbit and other vertebrates.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cav1.2 Antibody [HRP]

  • alpha-1 subunit
  • calcium channel, voltage-dependent, L type, alpha 1C subunit
  • cardic dihydropyridine-sensitive, alpha-1 subunit
  • L type, alpha 1 polypeptide, isoform 1, cardic muscle
  • L type, alpha-1 polypeptide, isoform 1, cardiac muscle
  • splice variant 10*

Background

CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol CACNA1C