Casein Kinase 1 epsilon Antibody

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Western Blot: CSNK1E Antibody [NBP1-52951] - THP-1 cell lysate, concentration 0.2-1 ug/ml.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-52951
    • Availability
      Product Discontinued

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Casein Kinase 1 epsilon Antibody Summary

Immunogen
Synthetic peptides corresponding to CSNK1E(casein kinase 1, epsilon) The peptide sequence was selected from the N terminal of CSNK1E. Peptide sequence MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLH.
Clonality
Polyclonal
Host
Rabbit
Gene
CSNK1E
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against CSNK1E and was validated on Western blot.
Theoretical MW
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Casein Kinase 1 epsilon Antibody

  • Casein Kinase 1 epsilon
  • casein kinase 1, epsilon
  • casein kinase I isoform epsilon
  • CKIe
  • CKI-epsilon
  • CSNK1E
  • EC 2.7.11
  • EC 2.7.11.1
  • HCKIE
  • MGC10398

Background

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CSNK1E can phosphorylate a large number of proteins. CSNK1E participates in Wnt signaling and is the central component of the circadian clock. It may act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. CSNK1E inhibits cytokine-induced granuloytic differentiation.The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. This protein has been shown to phosphorylate period, a circadian rhythm protein. Two transcript variants encoding the same protein have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSNK1E
Entrez
Uniprot