CARF/CDKN2AIP Antibody [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 350

CARF/CDKN2AIP Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human CARF
  Ser379-Leu579
  Accession # Q9NXV6
• Specificity: Detects human CARF in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CARF/CDKN2AIP Antibody [Alexa Fluor® 350]

• CARF
• CARFCDKN2A-interacting protein
• CDKN2A interacting protein
• CDKN2AIP
• collaborates/cooperates with ARF (alternate reading frame) protein
• Collaborator of ARF
• FLJ20036

Background

CARF (collaborator of ARF) is a component of the ARF-MDM2-p53 pathway. CARF interacts with ARF in the nucleolus accentuating ARF-mediated p53 stabilization and activation. Data also suggests that in the absence of ARF, CARF interacts directly with p53 in the nucleoplasm resulting in a moderate stabilization and activation of p53.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.