Cardiotrophin-1/CT-1 Antibody

Images

 
Western Blot: Cardiotrophin-1/CT-1 Antibody [NBP1-51255] - Analysis of CT-1 (H31) pAb at 1:500 dilutionLane1:Hela cell lysateLane2:Mouse liver tissue lysateLane3:Rat liver tissue lysate
Immunohistochemistry-Paraffin: Cardiotrophin-1/CT-1 Antibody [NBP1-51255] - Analyzes of Cardiotrophin-1 (H31) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Western Blot: Cardiotrophin 1 Antibody [NBP1-51255] - Analyzes of Cardiotrophin 1 (H31) pAb in extracts from HUVEC cells.
Immunohistochemistry-Paraffin: Cardiotrophin 1 Antibody [NBP1-51255] - Human lung carcinoma tissue.

Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-51255
    • Availability
      Product Discontinued

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Cardiotrophin-1/CT-1 Antibody Summary

Immunogen
Synthetic peptide, corresponding to amino acids 1-53 of Human CT-1.
Specificity
Cardiotrophin-1 (H31) pAb detects endogenous levels of Cardiotrophin-1 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
CTF1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin 1:50-1:200
Application Notes
Western blot (WB) analyzes of Cardiotrophin-1 (H31) pAb in extracts from HUVEC cells.
Immunohistochemistry (IHC) analyzes of Cardiotrophin-1 (H31) pAb in paraffin-embedded human lung carcinoma tissue.
Theoretical MW
21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2)
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cardiotrophin-1/CT-1 Antibody

  • cardiophin 1
  • cardiotrophin 1
  • Cardiotrophin1
  • Cardiotrophin-1
  • CT-1CT1
  • CTF1

Background

Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development. Cardiotrophin-1 is highly expressed in heart, prostate, ovary and skeletal muscle. Lower levels of expression are seen in lung, kidney, pancreas, thymus, testis and small intestine.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Diseases for Cardiotrophin-1/CT-1 Antibody (NBP1-51255)

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Bioinformatics

Gene Symbol CTF1
Entrez